We're diagnosing a TCP packet re-transmission issue between our environment and a service provider. Our ISP has their switch in our entrance facility configured for jumbo frames. Our Cisco 5000 Nexus switch that hosts our WAN port and forwards the traffic on to our virtual firewall is also configured for jumbo frames. From the firewall back though, it's all MTU 1500.
Is this likely to cause packet loss when traffic picks up, and if adjustments need to be made should I be configuring every part of the network for or against jumbo frames, or can there be a termination point of sorts where jumbo stops and standard MTU settings resume?
Thank you for any insight into this issue. This network was configured before my time, and while it's my responsibility now, as a school IT tech I am responsible for so many different things it's difficult to know how to adjust more sensitive network settings mid-semester.
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