DirectPath I/O within VMware 6.5

Hello,

We have an environment with 3 VM hosts in vSphere. We are looking at implementing DirectPath I/O within VMware. Our setup is vmnic 4, 5, 6, and 7 are disabled at the moment and vmnic 0,1,2 and 3 are not supported. Does this mean that 0-3 we are not able to enable DirectPath I/O? If so, if we already have vmnic's setup i the environment will that cause an issue with configuring DirectPath I/O?

​

Thanks,